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Primary sternal osteomyelitis due to Peptostreptococcusanaerobius. Upper inset.This highermagnification of the microvilli shows the small endocytotic vesicles thathave pinched offfrom the plasma membrane at the base ofthe microvilli.X 32,000. The conformation of mutant p53 hasbeen shown to cause mutant p53 to bind to upregulated Hsp90, trapping it andMdm2 in a complex, preventing Mdm2 from ubiquitinating mutant p53 [ 23 ]. Progressivedemineralization in the MRI (Figure 15.3) or CT up to about 6 weeks is not an indicationof internal stabilization in a patient with vertebral osteomyelitis [66]. (2008b) Folate, vita-min B6, vitamin B12, and methionine intakes and risk of strokesubtypes in male smokers. Research that was conducted for the sakeof basic knowledge may turn out to have an important application

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